Detalhe da pesquisa
1.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 184(18): 4651-4668.e25, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450028
2.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 187(6): 1565-1566, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490183
3.
Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients.
Int J Mol Sci
; 21(15)2020 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32707880
4.
CD98hc is a target for brain delivery of biotherapeutics.
Nat Commun
; 14(1): 5053, 2023 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37598178
5.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Mol Neurodegener
; 17(1): 41, 2022 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35690868
6.
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.
Neuron
; 105(5): 837-854.e9, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31902528
7.
Author Correction: CD98hc is a target for brain delivery of biotherapeutics.
Nat Commun
; 14(1): 5516, 2023 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679403
8.
BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats.
Sci Rep
; 7: 44249, 2017 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28281673